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Research Scientist/Sr. Research Scientist - Biologics modelling

From: Masoud Jamei <masoud.jamei>
Date: Mon, 10 May 2021 20:17:58 +0100

Dear All


We have an immediate opening for a Research Scientist / Senior Research
Scientist who is keen to apply their skills in developing mechanistic models
for large drug molecules (biologics). We consider applicants anywhere in the
world and relocation to UK isn't essential.


Apply here: Research Scientist/Sr. Research Scientist | Certara | LinkedIn





More information .


The candidate should have a good understanding of physiologically based
pharmacokinetic/pharmacodynamic models. Ideally, these experiences should be
in areas related to pharmacokinetics, biodistribution, and pharmacodynamics
of therapeutic proteins or other modalities. This position is located in
Sheffield, UK or remote from home.

Evidence to show critical thinking and the ability to carry out research
independently is desirable. The post holder is expected to provide on-going
customer support and, after training, contribute to education and training
activities, and client interactions specifically related to the therapeutic
protein modules, and to act as a tutor on workshops.

The successful candidate will join an internationally recognised,
multidisciplinary research team, providing opportunities for further
development of knowledge and skills. The post does not include laboratory or
clinical work. We offer a unique and exciting mix of academic and commercial
environments, which encourage regular attendance at scientific meetings as
part of our continuous education programs.


Requirements :

. PhD or equivalent experience in pharmaceutical sciences,
pharmacology, control or chemical engineering or related fields with few
years of practical experience;

. In depth understanding of processes affecting therapeutic proteins
or other modalities disposition and experience in developing biological
and/or physiological PK/PD models;

. Publications in high impact factor journals;

. Good working knowledge of common or specialised modelling and
simulation languages e.g. Matlab, R, etc;

. Demonstrable communication skills, as evidenced by presentations
at scientific meetings and publications in scientific journals, and good
interpersonal and organizational skills


. Knowledge of in vitro in vivo extrapolation (IVIVE) techniques

. Experience in modelling of monoclonal antibodies and/or smaller

. Knowledge of bioanalysis and biotransformation of peptides,
proteins or other biologics

Company Overview

Simcyp is part of Certara, a company which combines sophisticated research
and development informatics with the power of predictive science
methodologies to span the drug development spectrum and offer pharma a
previously unavailable 'end-to-end' solution in the quest for improving
human health. The Simcyp team conducts cutting-edge research and provides
consultancy, knowledge integration tools, algorithms, modelling solutions
and databases (implemented in its globally-recognised Simcyp
Population-based Simulator) for a client base of major blue-chip
pharmaceutical and biotechnology organisations. Simcyp focuses, in
particular, on gathering information required for the modelling and
simulation (M&S) of the individual time-course and fate of drugs. We are on
course to become the global industry standard, consequently, there is a
continuous requirement for high quality people to join us, help in our
expansion and share in our success.

Certara bases all employment-related decision on merit, taking into
consideration qualifications, skills, achievement, and performance. We treat
all applicants and employees without regard to personal characteristics such
as race, color, ethnicity, religion, sex, sexual orientation, age,
nationality, marital status, pregnancy, physical or mental condition,
genetic information, military service, or other characteristic protected by

Received on Mon May 10 2021 - 15:17:58 EDT

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