NONMEM Users Network Archive

Hosted by Cognigen

AI/ML postdoc opportunity at AstraZeneca

From: Penland, Chris <Chris.Penland>
Date: Wed, 5 May 2021 20:05:15 +0000

Dear colleagues -

Please see the ML/AI post-doc opportunity below - within the Clinical Pharm=
acology & Pharmacometrics group at Astrazeneca.
Seeking a promising, energetic researcher interested in applying ML/AI to e=
xamine our substantial clinical trial database to develop insights into dis=
ease progression, patient segmentation, and therapeutic response in cardiov=
ascular, renal and metabolic diseases. While in the program, in our departm=
ent, you can also get exposure to the clinpharm/pharmacometrics staff and i=
ndustry.

Interested candidates can send their CV and note of interest to Dave Boulto=
n<https://www.linkedin.com/in/daveboulton/>, the Industrial Supervisor/ Ast=
raZeneca Hiring Manager, via email at: David.Boulton2
o:David.Boulton2
(Chris.Penland
ach out to me to discuss the project details.

Postdoc Fellow: Machine Learning to Predict CV and Renal Outcomes (R-099638=
)

Do you want your work to truly make a difference?

About the Postdoc Program:
We're currently looking for talented scientists to join our innovative acad=
emic-style Global Postdoc Program<https://careers.astrazeneca.com/postdocs-=
astrazeneca>. From our center in Gaithersburg, MD or Waltham, MA, you'll be=
 in a global pharmaceutical environment, contributing to live projects righ=
t from the start. You'll take part in a comprehensive training program, inc=
luding a focus on drug discovery and development, given access to our exist=
ing Postdoctoral research, and be encouraged to pursue your own independent=
 research working with cutting edge Machine Learning/Data Science tools.
What's more, you'll have the support of a leading academic advisor, who'll =
provide you with the guidance and knowledge you need to develop your career=
. This is an exciting area that hasn't been explored to its full potential,=
 making this an opportunity to make a real difference to the future of medi=
cal science.

About the Opportunity:
We will use artificial intelligence tools and computational modelling to pr=
edict individual long-term risk of major CV events (MACE) and renal disease=
 based on patient characteristics and short-term biomarker changes in a ver=
y large combined database of AstraZeneca's cardiovascular outcomes trials (=
patient-level data for ~180 000 individuals). This will facilitate treatmen=
t selection for patients with diabetes and cardiovascular disease by identi=
fying characteristics that predict therapeutic response or non-response to =
different drug classes, inform patient selection and outcome definitions fo=
r future CV and renal outcomes trials, and characterize disease progression=
 over time.
If this sounds like you, apply now!

Essential Education and Experience:

  * A PhD and/or a recent Postdoctoral fellowship in a quantitative disci=
pline (engineering, pharmacology, computational biology, applied math, or r=
elated)
  * Success demonstrated by scientific publications and conference presen=
tations.
  * Interest in applying quantitative tools to solve clinically-meaningfu=
l problems
*
Desirable Qualifications:

  * Working knowledge of biology and physiology
  * Experience working with clinical data
*
Skills and Capabilities:

  * Proficiency and hands-on experience with data analysis, machine learn=
ing, and/or computational modelling in R or similar software
  * Ability to communicate technical material to a broad audience
  * Proven track record of effectively working independently, as well as =
within a team, to achieve results
  * This is a 2-year program, which will be based in Gaithersburg, MD or =
Waltham (Boston), MA with a competitive salary/benefits on offer.

To Find Out More:

Contact Dave Boulton<https://www.linkedin.com/in/daveboulton/>, the Industr=
ial Supervisor/ AstraZeneca Hiring Manager, via email at: David.Boulton2
trazeneca.com<mailto:David.Boulton2

About AstraZeneca
AstraZeneca is a global, innovation-driven biopharmaceutical business that =
focuses on the discovery, development and commercialization of prescription=
 medicines for some of the world's most serious diseases. But we're more th=
an one of the world's leading pharmaceutical companies. At AstraZeneca, we'=
re proud to have an outstanding workplace culture that encourages innovatio=
n and collaboration. Here, employees are empowered to express diverse persp=
ectives - and are made to feel valued, energized and rewarded for their ide=
as and creativity.
________________________________
________________________________

Confidentiality Notice: This message is private and may contain confidentia=
l and proprietary information. If you have received this message in error, =
please notify us and remove it from your system and note that you must not =
copy, distribute or take any action in reliance on it. Any unauthorized use=
 or disclosure of the contents of this message is not permitted and may be =
unlawful.


Received on Wed May 05 2021 - 16:05:15 EDT

The NONMEM Users Network is maintained by ICON plc. Requests to subscribe to the network should be sent to: nmusers-request@iconplc.com.

Once subscribed, you may contribute to the discussion by emailing: nmusers@globomaxnm.com.