NONMEM Users Network Archive

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Problem with PSN4. 9 - COVARIANCE STEP ABORTED

From: Shankar Lanke <shankarlanke>
Date: Mon, 3 May 2021 12:45:06 -0400

Dear NMUsers,

I am having trouble with PSN4.9, if anyone has a similar issue may I know
how to fix it?

I ran a model that was developed prior to the release of PSN4.9. In PSN4.9
the covariance step is aborted because S Matrix is unobtainable. I purged
4.9 and loaded 4.8, the model ran perfectly and matched the
previous results. Thank you very much in advance.



*Version 4.9*

 #TERE:

Elapsed estimation time in seconds: 633.22

0S MATRIX UNOBTAINABLE

0COVARIANCE STEP ABORTED

Elapsed covariance time in seconds: 47.98

Elapsed postprocess time in seconds: 51.79



 *Version 4.8*

#TERM:

0MINIMIZATION SUCCESSFUL

 NO. OF FUNCTION EVALUATIONS USED: 783

 NO. OF SIG. DIGITS IN FINAL EST.: 2.0



Regards,

Shankar Lanke

Received on Mon May 03 2021 - 12:45:06 EDT

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