NONMEM Users Network Archive

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Time-varying input/flexibility to change input rate on the fly

From: Robin Michelet <robin.michelet>
Date: Fri, 6 Aug 2021 21:38:17 +0200

Dear all,

I was wondering if any progress has been made on the topic raised
originally by Bill Denney in 2018:

https://www.mail-archive.com/nmusers

Are there any simpler ways in NM 7.5 to adapt input (e.g. infusion
rates) in $DES during the integration step without adapting the dataset
itself? I.e. to model the malfunctioning of an infusion pump (at
random), the loss of part of a tablet, or the detachment of a patch?

Thank you! I could not answer to the original topic which is why I just
linked to it.

--
Dr. ir. Robin Michelet
Senior scientist

Freie Universitaet Berlin
Institute of Pharmacy
Dept. of Clinical Pharmacy & Biochemistry
Kelchstr. 31
12169 Berlin
Germany
Phone: + 49 30 838 50659
Fax: + 49 30 838 4 50656
Email: robin.michelet
www.clinical-pharmacy.eu
https://fair-flagellin.eu/

Received on Fri Aug 06 2021 - 15:38:17 EDT

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