NONMEM Users Network Archive

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OFV from different algorithms

From: Mark Tepeck <mark.tepeck>
Date: Wed, 23 Sep 2020 17:09:45 -0700

Hi NMusers,

I believe below is a very common question, but I could not find a
clear answer in literature.

Sometimes, we want to find out which algorithm offers the better model
fitting for a given dataset.

Is it possible to use the objective function value (OFV) to compare
the model fitting computed by various algorithms (e.g. FOCE, IMP, and
SAEM) ? Put it into another way, the same input dataset with the same
fitted model/estimates will lead to similar OFVs among FOCE, IMP, and


Received on Wed Sep 23 2020 - 20:09:45 EDT

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