NONMEM Users Network Archive

Hosted by Cognigen

Re: MPI excusion issues with NM7.4

From: Saeheum Song <ss.pkpdmodel>
Date: Thu, 14 May 2020 21:29:30 -0400

Dear Nonmem USERS,

Through the day, I finally configured out what was happening.
(1) NONMEM with and without MPI seem to run a little differently. This
observation is based on the following experience.

I have ran the same code without MPI, it ran through with NSIG errors. I
have replaced initial estimates with output without MPI.
I have success in running MPI module. The only one is that I need to use
pnm file from NONMEM 72 file. A little strange.

Thanks for help.


On Thu, May 14, 2020 at 2:20 PM Saeheum Song <ss.pkpdmodel

> Dear Henning,
>
> Thanks for the kind reply. I tried but resulted the same error. Also
> NONMEM has been detected in firewall for version 7.4.
>
> Hope to find solution soon.
>
> Kind regards.
>
>
> On Thu, May 14, 2020 at 1:05 PM Henning Schmidt <
> henning.schmidt
>
>> Hi,
>>
>> The issue with "HKEY_LOCAL_MACHINE\SAFTWARE\MPHCH\SMPD\Process\34068" is
>> easily solved by starting regedit in Windows, navigating to
>> HKEY_LOCAL_MACHINE\SAFTWARE\MPHCH\SMPD , right click on SMPD and select
>> "Permissions". Give all users "Full Control" and you are up and running in
>> parallel.
>>
>> You need admin rights for it.
>>
>> Best,
>> Henning
>>
>> PS: Below the para file that I use on Windows since 7.3 (also in 7.4) -
>> no claim of optimality - but it works
>>
>> $DEFAULTS
>> [nodes]=4
>>
>> $GENERAL
>> NODES=[nodes] PARSE_TYPE=2 PARSE_NUM=100 TIMEOUTI=100 TIMEOUT=2000
>> PARAPRINT=0 TRANSFER_TYPE=1
>>
>> $COMMANDS ;each node gets a command line, used to launch the node session
>> 1:mpiexec -wdir "%cd%" -localonly -n 1 nonmem.exe %*
>> 2-[nodes]:-wdir "%cd%\worker{#-1}" -n 1 nonmem.exe
>>
>> $DIRECTORIES
>> 1:NONE ; FIRST DIRECTORY IS THE COMMON DIRECTORY
>> 2-[nodes]:worker{#-1} ; NEXT SET ARE THE WORKER directories
>>
>> $IDRANGES ; USED IF PARSE_TYPE=3
>> 1:61,100
>> 2:1,60
>>
>>
>> ________________________________________________________________________________
>>
>>
>>
>> IntiQuan GmbH
>> Elisabethenstrasse 23 [see map] <https://goo.gl/maps/x5WM2wVdXK8qcn8c6>
>> 4051 Basel, Switzerland
>> Web: www.intiquan.com
>> Tel: +41 76 603 28 06
>>
>> *Confidentiality Note: *This message is intended solely for the
>> designated recipient(s). It may contain confidential or proprietary information
>> and may be subject to attorney-client privilege or other confidentiality
>> protections. If you are not a designated recipient you may not review, copy
>> or distribute this message. If you receive this in error, please notify the
>> sender by reply e-mail and delete this message. Thank you.
>>
>> *Data Protection & Privacy:* The IntiQuan Data Protection statement
>> applies for all communication. You can view it here:
>> https://www.intiquan.com/data-protection.
>>
>> IntiQuan GmbH | Managing Director: Dr. Henning Schmidt | Trade register:
>> Basel Stadt CH-270.4.004.907-8 | UID: CHE-181.306.905
>>
>>
>> On Thu, May 14, 2020 at 6:53 PM Saeheum Song <ss.pkpdmodel
>> wrote:
>>
>>> Dear Nonmem users,
>>>
>>> I have tried to use MPI for nonmem 7.4, it resulted in quit from all
>>> users, while MPI successfully run for nm7.2.
>>> with command lines of
>>> C:\Strawberry\perl\bin/execute -parafile=c:\nm72g\run\mpiwini8.pnm
>>> -nm_version=nm74 -nodes=6 -picky -retries=10 ARS_IN_D_TY2_ALL.mod
>>>
>>> C:\Strawberry\perl\bin/execute -parafile=c:\nm72g\run\mpiwini8.pnm
>>> -nm_version=nm72 -nodes=6 -picky -retries=10 ARS_IN_D_TY2_ALL.mod
>>>
>>> I have to use parafile from nm72 parafile from nm74 did not work.
>>>
>>> Error Comments were QUIT Signal From Worker1..5.
>>>
>>> When I use parafile in nm74. error messages are
>>> unable to open the HKEY_LOCAL_MACHINE\SAFTWARE\MPHCH\SMPD\Process\34068,
>>> error 5, Access denied.
>>>
>>> The my nonmem code successfully run at nmfe74 command.
>>>
>>>
>>> Any suggestions?,
>>>
>>> Kind regards,
>>>
>>

Received on Thu May 14 2020 - 21:29:30 EDT

The NONMEM Users Network is maintained by ICON plc. Requests to subscribe to the network should be sent to: nmusers-request@iconplc.com.

Once subscribed, you may contribute to the discussion by emailing: nmusers@globomaxnm.com.