NONMEM Users Network Archive

Hosted by Cognigen

Introduction course to Population PK and PK/PD modelling with NONMEM

From: Stevens, J <j.stevens>
Date: Thu, 13 Feb 2020 13:33:44 +0000

Introduction course to Population PK and PK/PD modelling with NONMEM
During this three days course, participants will be introduced to the basic=
 principles of population approach nonlinear mixed effects modelling in pha=
rmacokinetic (PK) and pharmacodynamic (PD) evaluation of drugs and will hav=
e opportunities for hands-on PK and PK/PD modelling and simulation examples=
 relevant to drug development. Topics include how to work with NONMEM and R=
, data file preparation, model coding and visualization/interpretation of t=
he results.

Target audience
The course is intended for people who have a basic knowledge of PK, PD and =
data analysis, and wish to extend their knowledge and skills on PK/PD in dr=
ug development.

Course objectives
Aim of the course is to familiarize the participants with the basics of pop=
ulation PK/PD modelling and to train the participants in working with NONME=
M to conduct population PK and PK/PD data analyses.

Instructor Dr. Jasper Stevens
Duration 3 x 8 hours
Dates 6, 7 and 8 May 2020; 09:00-17:00
Location University Medical Center Groningen,=
 Groningen, The Netherlands
Language English
Maximum capacity 16 participants

Course overview
Session 1 Introduction to population PK modelling, NONMEM and R
Session 2 NONMEM work flow for population PK models; data manag=
ement, data exploration, model code and execution, output and interpretatio=
Session 3 Population PK models continued: alternative administr=
ation routes, solving differential equations using NONMEM and simulations
Session 4 Population PK/PD models: introduction to PK/PD models=
 and implementation of direct effect models in NONMEM
Session 5 Population PK/PD models: effect compartment and indir=
ect response models

Course fee
The course fee is 1200 EUR, including course materials, coffee breaks, lunc=
hes and one evening dinner (Wednesday evening). Computers are available, in=
cluding the required software packages.
A limited number of (PhD) students can register for a reduced fee (600 EUR)=
, for which a support letter of the supervisor has to be included upon regi=
Cancellation received before April 10th, 2020 is subject to full refund, ca=
ncellation received after this date is subject to 50% refund.

To register for the course, please send an email to nonmem

Jasper Stevens, PhD
University Medical Center Groningen
Clinical Pharmacy and Pharmacology
De Brug 50.1.D.15A; EB70
PO Box 30001
9700 RD Groningen
Tel: +31 50 361 7875
Fax: +31 50 361 4087

De inhoud van dit bericht is vertrouwelijk en alleen bestemd voor de geadre=
sseerde(n). Anderen dan de geadresseerde(n) mogen geen gebruik maken van di=
t bericht, het niet openbaar maken of op enige wijze verspreiden of vermeni=
gvuldigen. Het UMCG kan niet aansprakelijk gesteld worden voor een incomple=
te aankomst of vertraging van dit verzonden bericht.

The contents of this message are confidential and only intended for the eye=
s of the addressee(s). Others than the addressee(s) are not allowed to use =
this message, to make it public or to distribute or multiply this message i=
n any way. The UMCG cannot be held responsible for incomplete reception or =
delay of this transferred message.

Received on Thu Feb 13 2020 - 08:33:44 EST

The NONMEM Users Network is maintained by ICON plc. Requests to subscribe to the network should be sent to:

Once subscribed, you may contribute to the discussion by emailing: