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WCoP Workshop: Open Source Pharmacometrics Open for registration

From: Matthew Fidler <matthew.fidler>
Date: Wed, 5 Feb 2020 13:03:09 -0600

An open-source Pharmacometrics’s workflow in R: from exploration (x=
Gx) to
model building (nlmixr) and diagnostics (ggPMX)

Sponsored by Novartis and co-hosted by Pharmacometrics Africa
<>, NPC

Workshop target audience:

Pharmacometricians/modelers with basic knowledge on model building,
evaluation and qualification. Basic knowledge of writing, executing R
scripts is advantageous.

Workshop faculty:

Fariba Khanshan, Novartis Pharmacometrics, Cambridge, USA
Matt Fidler, Novartis Pharmacometrics, Fort Worth, USA
Irina Baltcheva, Novartis Pharmacometrics, Basel, Switzerland


The workshop will provide a tutorial on three open–source R package=
currently under development at Novartis, supporting the pharmacometrics
workflow in exploring and modelling clinical data:

   - Exploration of the data using the Exploratory Graphics (xGx) package,
   available on GitHub (
   - Population PK and PKPD modelling of the data using nlmixr ( <>). nlmixr
   builds on the ODE solving in the RxODE package, by implementing paramete=
   estimation algorithms like nlme, SAEM and FOCE with interaction.
   - Model building and validation using ggPMX, a library of reproducible
   diagnostic plots available on CRAN and on Github (https

The combination of the three open-source R packages provides the
pharmacometrics modelling community the opportunity to reduce the learning
curve needed to become proficient on each of the different tasks using a
stepwise framework.


$25 / R400

Click here for more info

Click here to register <>

Received on Wed Feb 05 2020 - 14:03:09 EST

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