NONMEM Users Network Archive

Hosted by Cognigen

Postdoctoral research fello position at FU Berlin

From: Michelet, Robin <robin.michelet>
Date: Mon, 25 Nov 2019 16:03:58 +0100

----The Department of Clinical Pharmacy and Biochemistry of the
Institute of Pharmacy at the Freie Universitaet Berlin is currently
lookingfora: Postdoctoral Research Fellow(m/f/d)---

We are an interdisciplinary, international, research-oriented group
applying high scientific standards and innovative methodologies with the
ultimate aim to foster the rational use of medicines while empowering
young scientists to perform clinically relevant research
( <>).
Our group is grounded on two research pillars: (1) Bioanalysis,
microdialysis, cell culture, and (2) Pharmacometric (data) analysis. As
key feature, the two pillars are bridged, as our pharmacometric projects
are based on in vivo or in vitro data obtained by the experimental
research pillar, while innovative dynamic in vitro systems utilise
modelling and simulation approaches. In addition, many of our projects
are realised as parts of clinical studies. Typically, our research is
embedded in consortia at a national and international level (EU, global).

We are looking for a full-time postdoctoral fellow in the field of
optimising drug therapy and drug development by applyinginnovative
translationalmodelling and simulation techniquesto join our research
group for a period of at least 2year; extension to 5 years is possible.
To be eligible for the position, a PhD and a strong record in the
pharmacometric research area is needed. Additionally, experience in
either or (i) evaluating pharmacokinetic, pharmacodynamic or systems
pharmacology data and pharmacometric analysis with NONMEM, R or similar
pharmacometric software,(ii) Bayesian analysis using STAN,or (iii) one
of our experimental platforms (LC/MS-MS, microdialysis, bacterial
infection models, in vitro metabolism)is required.

The position also offer supervision of PhD and Master/Diploma students.
Applications in English should include a letter of motivation incl. a
description of research interests and relevant qualifications for the
position. In addition, a curriculum vitae including a list of
publications and names/email addresses of 2-3 referees should be provided.

Please submit your application to: charlotte.kloft

----Job profile----

•Performance and publication of research projects in pharmacometric and
translational modelling

•Contribution to EU project “FAIR” of the Horizon 2020 initiative(11
European partnersfrom 6 different countries; Work package 5: Development
of a translational modelling and simulation platform for flagellin PK/PD )

• Contribution to conception and realisation of new research ideas and
collaborations•General services in research (co-supervision of junior
members; IT/Cluster contact) and research organisation

----Qualification profile----


• Graduation in Pharmaceuticalor Life sciencesor related field

• Qualified PhD thesis in pharmacometrics, systems pharmacology or
PBPK(PD) modelling, preferentially PK/PD modelling of therapeutic proteins


• Profound knowledge in pharmacometrics software: e.g. NONMEM/PsN,

• Goodknowledge in the software programs R, PKSim,STAN, Monolix, Pirana

• In-depth experience in organisation and performance of research
projects and in scientific publication in the area of pharmacometrics

• Experience with or interest for in vitrowork such as bacterial
infection models, in vitro microdialysis or in vitro metabolism experiments

• High intrinsic motivation/high level of commitment

• Excellent team player

• Strong verbal/written communication skills

• Language skills: English excellent, no German required.

Dr. ir. Robin Michelet
Senior scientist

Freie Universitaet Berlin
Institute of Pharmacy
Dept. of Clinical Pharmacy & Biochemistry
Kelchstr. 31
12169 Berlin
Phone: + 49 30 838 50659
Fax: + 49 30 838 4 50656

Received on Mon Nov 25 2019 - 10:03:58 EST

The NONMEM Users Network is maintained by ICON plc. Requests to subscribe to the network should be sent to:

Once subscribed, you may contribute to the discussion by emailing: