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Associate Director, Pharmacokinetics / Pharmacokinetic Scientist - Anywhere, US

From: felix boakye-agyeman <boakyefe>
Date: Wed, 12 Jun 2019 01:59:48 -0400

Associate Director, Pharmacokinetics / Pharmacokinetic Scientist -
Anywhere, US

*Office-based or Remote-based*

Who We Are

Synteract is a global full-service contract research organization with a
successful three-decade track record supporting biotechnology, medical
device and pharmaceutical companies. With our mission of ”Bringing =
Trials to Life,” we provide customized Phase I through IV services
internationally, offering expertise across multiple therapeutic areas
including notable depth in Oncology, Neuro Degenerative Diseases, and Rare
and Orphan Diseases, and in pediatric populations. Our mission is to
support the innovation and development of better therapies in healthcare.

*Position Overview*

The Associate Director, Pharmacokinetics / Pharmacokinetic Scientist
conducts PK/PD modeling and population PK analyses using WinNonLin, NonMem
and PKSim with a focus on designing optimal dosing regimens for pediatric
patients and other special patient populations. Provide pharmacology,
pharmacokinetic consulting to clients with a specialization on pediatric
patient populations. Design, analyze and report pre-clinical and clinical
pharmacokinetic, PK/PD modeling and trial simulation studies. Be the
subject-matter expert on pediatric dosing methodologies including
allometric scaling approaches.

Specific tasks would include:

   - Conduct PK/PD analyses, modeling and simulation in WinNonLin, NonMem
   and PK-Sim for pediatric patients other special patient populations
   requiring dose regimen modification.
   - Assist clients in the design and development of pre-clinical and
   clinical protocols with respect to toxicokinetic and pharmacokinetic
   analyses ·
   - When the lead PK Scientist on assigned projects, act as the project
   manager to include functioning as the principal liaison with key clients=
   vendors, and internal team members.
   - When the lead PK Scientist, will create trust and confidence amongst
   clients, vendors and team members while delivering on-time, and on-budge=
   programs that leverage the various resources, expertise and cross functi=
   knowledge available within Synteract.
   - Work with client’s data management group to prepare datasets f=
   import and analysis in WinNonLin.
   - Conduct non-compartmental (NCA) and compartmental PK analysis is
   Phoenix WinNonLin-PKSo.
   - Responsible for locking and unlocking studies/scenarios in the PKSo
   database following management authorization.
   - Writing stand-alone PK reports and PK study report sections for CSR=
s ·
   - Responsible for ensuring study data and study reports are retained
   according to the corporate records retention policy. ·
   - Ensuring corporate quality policies and SOPs are followed during the
   analysis and reporting of PK studies ·
   - Provide pharmacology, pharmacokinetic and drug development consulting
   services to clients with a specialization in pediatric drug development.


   - Ph.D. in Pharmacokinetics or Pharmaceutical Sciences, plus knowledge
   of how to support pediatric Pharmacokinetic/Pharmacodynamic modeling and
   simulations, specifically population PK.
   - Pediatric knowledge can be gained concurrently through Ph.D. program,
   as a postdoctoral fellow, or in a professional position.
   - 10% domestic travel to meetings/conferences/client sites
   - If you’re passionate about bringing clinical trials to life, w=
   encourage you to apply today!

Synteract’s policy is to provide equal employment opportunity and
affirmative action in all of its employment practices without regard to
race, color, religion, sex, national origin, ancestry, marital status,
protected veteran status, age, individuals with disabilities, sexual
orientation or gender identity or expression or any other legally protected
category. Applicants for positions with Synteract must be legally
authorized to work in the country which they are applying and verification
of employment eligibility will be required as a condition of hire.

> Please contact me at felix.boakye-agyeman
interested or have any questions
Warm Regards,

*Felix Boakye-Agyeman, M.D., Ph.D.*

Director, Pharmacokinetics |* synteract*®


Received on Wed Jun 12 2019 - 01:59:48 EDT

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