NONMEM Users Network Archive

Hosted by Cognigen

Registration is open to the Convolution-based modeling workshop

From: roberto gomeni <roberto.gomeni>
Date: Fri, 25 Jan 2019 14:34:41 +0100

Workshop on Convolution-based modeling approach

March 11-13, 2019: Fort Lauderdale, FL (USA)


This three-day, hands-on course provides a working knowledge of the theories
and application of the state-of-the-art convolution-based modeling approach
to characterize complex PK profiles, to establish in-vitro in-vivo
correlation (IVIVC) and to optimize ER and LAI formulation development using
the exposure-response relationship.


Supportive material for the workshop can be found in our recent paper
published in the CPT Pharmacometrics Syst Pharmacol journal:


Interactive and real life examples, taken from actual industry experience
using R and NONMEM will be presented and discussed in the hands-on sections
to illustrate how to deal with delayed, multiple peaks and time dependent
absorption process, how to establishing a Level A IVIVC using a
model-informed approach and how to develop optimized formulations with an
in-vivo drug release suitable to maximize the clinical benefit of a


Who Should Attend?

The workshop is designed for pharmaceutical scientists, pharmacologists,
physicians and other scientists involved in drug development wishing to
learn and apply pharmacometrics as innovative decision supporting tool for
accelerating drug discovery and development.


What Will You Learn?

Upon completion of this course, you should have a solid understanding of how
to implement convolution-based models using NONMEM, how to implement IVIVC
using NONMEM, how to simulate drug exposure as a function of the modified
in-vivo delayed and time dependent drug release properties of ER and LAI
formulations using R, and how to optimize the properties of ER and LAI
formulations for maximizing the clinical benefit of a treatment.



Fort Lauderdale Marriott Harbor Beach Resort & Spa, 3030 Holiday Drive, Fort
Lauderdale, FL 33316 USA



For additional information, visit our website:



Roberto Gomeni, PhD.


Longcol, 12270 La Fouillade (France)

E-mail: <mailto:roberto.gomeni
roberto.gomeni <>

Next workshops on pharmacometrics:


Received on Fri Jan 25 2019 - 08:34:41 EST

The NONMEM Users Network is maintained by ICON plc. Requests to subscribe to the network should be sent to:

Once subscribed, you may contribute to the discussion by emailing: