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Quantitative Clinical Pharmacology Position at GSK

From: Chao Chen <chao.c.chen>
Date: Mon, 15 Apr 2019 21:02:55 +0000

GlaxoSmithKline (GSK) has an exciting position for a highly motivated Quant=
itative Clinical Pharmacologist to join our London team as a member of the =
global department of Clinical Pharmacology Modelling & Simulation. The job =
level will depend on the skills and achievements of the successful candidat=
e. This is an excellent opportunity to use quantitative clinical pharmacolo=
gy to accelerate the delivery of new medicines to patients by enhancing dru=
g program efficiency and business decision quality.
* Plan, execute and report translational drug-disease modelling, expo=
sure-response analysis, simulation-based trial design and population clinic=
al pharmacology
* Contribute to asset clinical development and registration in terms =
of program plans, trial protocols, analysis plans, study reports and regula=
tory submissions
* Assess and apply innovative techniques such as longitudinal exposur=
e-response analysis, model-based meta-analysis and item-response analysis t=
o maximise data use, trial efficiency and analytical power
* Present strategy and discuss outcome of model-based approaches duri=
ng interactions with internal governance boards and regulators
* Promote model-informed drug discovery and development through exter=
nal collaboration, journal publication and conference presentation

* A doctorate in a field relevant to quantitative clinical pharmacolo=
gy, and experience in using modelling/simulation to solve practical problem=
s in industry or academia
* Proven skills in pharmacokinetic-pharmacodynamic and longitudinal d=
isease modelling; and verifiable proficiency in pharmacometric tools NONMEM=
, Monolix, R or SAS
* Strong drive and learning agility to quickly build knowledge on a d=
rug-disease system, symptom progression, trial design/endpoints and current=
* Demonstrated aptitude for productive collaboration in a multi-disci=
pline team, using effective communication and taking personal accountabilit=
y for timely delivery of results
* Clear evidence of ability to make sound judgement in complex situat=
ions and adapt to changing business needs by prioritising multiple tasks

At GSK, we develop therapies of various modalities for a broad range of ind=
ications. As a member of a global department with diverse expertise, you wi=
ll enjoy a highly supportive environment for scientific innovation, busines=
s impact and professional growth. Interested persons are encouraged to appl=
y online here<
Chao Chen
Clinical Pharmacology Modelling & Simulation
GlaxoSmithKline R&D

GSK monitors email communications sent to and from GSK in order to protect =
GSK, our employees, customers, suppliers and business partners, from cyber =
threats and loss of GSK Information. GSK monitoring is conducted with appro=
priate confidentiality controls and in accordance with local laws and after=
 appropriate consultation.


This e-mail was sent by GlaxoSmithKline Services Unlimited
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member of the GlaxoSmithKline group of companies. The
registered address of GlaxoSmithKline Services Unlimited
is 980 Great West Road, Brentford, Middlesex TW8 9GS.

Received on Mon Apr 15 2019 - 17:02:55 EDT

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