NONMEM Users Network Archive

Hosted by Cognigen

[NMusers] Webinar: System Level Modeling of the Human Gut Microbiome

From: Rebecca Baillie <rbaillie_at_rosaandco.com>
Date: Tue, 11 Sep 2018 20:12:34 +0000

System Level Modeling of the Human Gut Microbiome

Prasad Dhurjati, PhD
 Professor of Chemical & Bio-molecular Engineering, Joint appointment as Professor Biological Sciences and Professor of Mathematical Sciences, University of Delaware
 
Thursday, September 20, 2018, 12:00 pm to 1:00 pm EDT

Register for free at https://www.rosaandco.com/webinars

Abstract:
The human gut is host to a diverse and complex ecosystem of over a thousand microorganisms that are collectively known as the " gut microbiome". The gut microbiome has already been correlated with over a hundred diseases and has created a revolution in medical science. These microbes play a major role in providing nutrition for our body and maintaining a strong immune system.

 Modeling of the spatiotemporal dynamics of the microbes is useful to investigate how the gut microbiome may influence "disease progression". The models could also help in designing strategies to dynamically manipulate the system trajectory away from a "disease" state to a "healthy" state. The importance of microbial dynamics will be illustrated in the context of our research on Autism Spectrum Disorders (ASD). System level modeling approaches using connectivity maps, rules, and mathematical equations have provided insights into the dynamic changes in the gut microbiome in ASD. Such system-level approaches can potentially be used for personalized and predictive diagnoses and for preventive nutritional recommendations.

Received on Tue Sep 11 2018 - 16:12:34 EDT

The NONMEM Users Network is maintained by ICON plc. Requests to subscribe to the network should be sent to: nmusers-request@iconplc.com. Once subscribed, you may contribute to the discussion by emailing: nmusers@globomaxnm.com.