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Opening position in PBPK at SERVIER (France)

From: marylore.chenel
Date: Thu, 17 May 2018 14:20:51 +0000

Servier is an international pharmaceutical company governed by a non-profit=
 Foundation and headquartered in France.
With a strong international presence in 148 countries and a turnover of 4 b=
illion euros in 2016, we employ over 21,000 people worldwide.
Being completely independent, we reinvest 25% of turnover (excluding generi=
cs) in Research and Development and use all our profits in growth.
We are specialized and driven by our constant search for innovation in five=
 major research areas: cardiovascular diseases, cancers, diabetes, immuno-i=
nflammatory diseases and neurodegenerative diseases, as well as by our acti=
vities in high-quality generic drugs.
Currently, we have 23 drug candidates including 19 new molecular entities a=
t various stages of clinical development.
Our priorities are pathologies with high medical needs within our areas of =

Company Strategy & 2020 Goals
- Increase Research output : launch on the market one new molecular en=
tity every 3 years
- Achieve sales of 5 billion Euros
- Become a key player in oncology and reinforce the group's presence i=
n its historical therapeutic areas, especially cardiology.


The Centre of Excellence in Pharmacokinetics (CentEx PK) at Servier has an =
opening position for a Physiological Based PK modelling (PBPK) scientist. T=
he position is open for both junior and confirmed scientists, with responsi=
bilities adapted to the experience.

The candidate will be full-time dedicated to modelling activities to suppor=
t pre-clinical and clinical development programmes. The candidate will have=
 strong relationships with other modellers in pharmacometrics (i.e. early p=
hase and late phase popPK & PKPD modelling) and stakeholders within and out=
side Servier (i.e. clinicians, pharmacologists, partners, CRO etc...).


The candidate will be responsible for:

· Defining the modelling strategy in collaboration with other pro=
ject members.

· PBPK model building and evaluation

· PBPK applications (simulations and extrapolation)

· Data analysis and simulation plan, reports

· Presenting PBPK activities to internal/external experts in the =

According to his/her experience, the candidate will also participate to:

· The improvement of modelling tools and methodological developme=

· Junior mentoring in pharmacometrics

· Promotion of modelling activities within the Servier group

Skills and Experience

You hold a PhD in a relevant area (PKPD/PBPK modeling, Biological Sciences,=
 Pharmacology, Engineering, Pharmaceutical Sciences or other related discip=
line). This position in PBPK requires a good knowledge of PBPK software suc=
h as SimCYP, GastroPlus or PKSim. Knowledge in Matlab is an asset.

You are fluent in English, both orally and written, and have good communica=
tion and presentation skills. The pharmacometrics group at Servier is locat=
ed in France (Suresnes near Paris and Orléans). Working knowledge of Fren=
ch is not a requirement.

You have an analytical mind-set and a strong desire to further develop and =
apply modelling and simulation in drug development. You appreciate working =
in teams of scientists with different backgrounds and the opportunity of ex=
panding your network at an international level.
We offer an exciting opportunity for developing your professional skills an=
d for working with projects with many challenges and with support from a ra=
nge of highly skilled professionals.

For further information, please contact Marylore Chenel: marylore.chenel

Marylore CHENEL
Clinical Pharmacokinetics and Pharmacometrics
Mobile +33 (0)6 70 07 25 36 - Phone. +33 (0)1 55 72 38 56
50, rue Carnot 92284 - Suresnes, France<>

Received on Thu May 17 2018 - 10:20:51 EDT

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