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Using Root-finding techniques to find Cmax/Tmax

From: Bauer, Robert <Robert.Bauer>
Date: Mon, 14 May 2018 15:55:27 +0000

Dear nmusers:
Because of the recent discussions (topic "Cmax/Tmax in the DES block") on t=
he proper way of obtaining tmax and cmax with ODE solvers, I have been moti=
vated to provide some examples utilizing root-finding techniques available =
in ADVAN14 (CVODES) and ADVAN15 (IDAS). Please read the cmax_root_finder.=
pdf, and view the accompanying example files, located in

Robert J. Bauer, Ph.D.
Senior Director
Pharmacometrics R&D
ICON Early Phase
820 W. Diamond Avenue
Suite 100
Gaithersburg, MD 20878
Office: (215) 616-6428
Mobile: (925) 286-0769
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Received on Mon May 14 2018 - 11:55:27 EDT

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