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RE: [NMusers] Cmax/Tmax in the DES block

From: Bauer, Robert <Robert.Bauer_at_iconplc.com>
Date: Sun, 6 May 2018 02:45:25 +0000

ADVAN6 does not overshoot. The others do. ADVAN8 does not have an option available to avoid overshoot (at least I could not find one looking through the code). ADVAN9, ADVAN13, ADVAN14 and ADVAN15 (all from Livermore Labs), have the ITASK option to control overshoot behavior, and I can have this option controlled at the control stream level.

Robert J. Bauer, Ph.D.
Senior Director
Pharmacometrics R&D
ICON Early Phase
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Robert.Bauer_at_iconplc.com<mailto:Robert.Bauer_at_iconplc.com>
www.iconplc.com<http://www.iconplc.com/>

From: Leonid Gibiansky [mailto:lgibiansky_at_quantpharm.com]
Sent: Saturday, May 05, 2018 9:00 AM
To: Bauer, Robert; nmusers_at_globomaxnm.com<mailto:nmusers_at_globomaxnm.com>
Subject: Re: [NMusers] Cmax/Tmax in the DES block

Thanks!
Looking on ADVAN6 code I cannot figure out whether it has the same
problem (with over-shooting the time interval). I guess not, could you
confirm?
Thanks
Leonid
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Received on Sat May 05 2018 - 22:45:25 EDT

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