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Summer internship: PKPD of siRNA therapeutics, Alnylam, Cambridge, MA

From: varun goel <varun_goel_9>
Date: Fri, 23 Mar 2018 02:08:46 +0000 (UTC)

Company Overview
Alnylam was founded in 2002 on a revolutionary vision and bold mission whic=
h remain firmly in place today. We are leading the translation of RNAi as a=
 new class of medicines with a core focus on RNAi therapeutics toward genet=
ically defined targets for the treatment of serious, life-threatening disea=
ses with limited treatment options for patients and their caregivers. In Ja=
nuary 2015, we announced our “Alnylam 2020” guidance that r=
eflects our expected transition from a late-stage clinical development comp=
any to a multi-product commercial-stage company with a sustainable developm=
ent pipeline. Alnylam is proud to have been recognized as one of The Boston=
 Globe’s Top Places to Work in 2015, 2016 and 2017.
Program DetailsWith RNAi technology, we have the opportunity to treat disea=
se and impact the lives of patients in a fundamentally new way. Alnylam Sum=
mer Internships are designed to develop practical biotech industry knowledg=
e and soft skill advancement, while contributing to the company’s o=
verall mission and goals.  As Alnylam heads towards commercialization,=
 there are a number of departments with meaningful internships available th=
at balance professional development and support organizational needs during=
 this exciting transition. Interns will also participate in companywide fun=
ctions such as Annual Community Service Day, Summer Outing, as well as even=
ts & development programs designed exclusively for students. Applicant=
s will be directed to choose from the following internships by area of inte=
rest: Research, Finance, Commercial & Marketing, Medical Affairs, Quality A=
ssurance, Manufacturing, Legal, Corporate Communications, Supply Chain, IT,=
 Clinical Development & Clinical Operations.
Qualifications·         You mu=
st be legally eligible to work in the U.S·    =
    The target start date is May 29 with an expected end =
date of mid/late August·       =
Must be currently enrolled in a Bachelors, Masters or PhD program (vari=
es by area)
Summer Intern Position in Clinical Pharmacology and Pharmacometrics Jo=
b Description:Through this program, intern will gain experiencein util=
ity of quantitative methods in supporting RNAi therapeutics fordrug develop=
ment of orphan disease indications. The students may interact withclinician=
s, biometrics, research, DMPK, or clinical pharmacology scientists.Dependin=
g on the interests of the interns following projects may be assigned·=
       Compartmental and PBPK modeling o=
f RNAitherapeutics·       Exposure-=
response modeling·       Systems ph=
armacology modeling of disease usingliterature and in-house data·=
      Statistical modeling of endpoints in=
forming trialoperating characteristics    Requirements:Currently =
enrolled in a PharmD, or MS/PhD degree program inPharmacometrics, Pharmaceu=
tical Sciences, Bioengineering, AppliedMathematics/Statistics, or a related=
 field. Eligible to work on a full-timebasis during the internship dur=
ation. Proficiency with quantitativesoftware e.g. Phoenix, R, and NONMEM St=
rong understanding of fundamentals of PKPD and hierarchicalmodeling of cont=
inuous and non-continuous endpoints. Exposure to Bayesianapproaches is high=
ly desirable.Visit the following link to apply Alnylam Summer Internsh=
ip Program 2018
| |
Alnylam Summer Internship Program 2018
 Click the link provided to see the complete job description. | |



Received on Thu Mar 22 2018 - 22:08:46 EDT

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