NONMEM Users Network Archive

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Tutorial on FOCE

From: Dong-Seok Yim <yimds>
Date: Tue, 17 Jan 2017 16:42:18 +0900



A tutorial "R-based reproduction of the estimation process hidden behind
NONMEMR Part 2: First-order conditional estimation" by Prof. Kyun-Seop Bae
was published to Transl Clin Pharacol 2016;24(4):161-168 weeks ago.
Previously, he published the same topic on the FO method. (Transl Clin
Pharacol 2015;23:1-7).

These tutorials let you learn how NONMEM calculates objective function
values through step-by-step reproduction using the R codes written by the
author. You may find a copy of the tutorial at its journal home:


Transl Clin Pharmacol is the official journal of the Korean Society for
Clinical Pharmacology and Therapeutics.


Best regards,


Dong-Seok Yim MD, PhD


Editor-in-Chief, Translational & Clinical Pharmacology

Director, PIPET (Pharmacometrics Institute for Practical Education &



Dept. of Pharmacology, College of Medicine The Catholic University of Korea

Dept. of Clinical Pharmacology and Therapeutics, Seoul St. Mary's Hospital

Office: +82-2-2258-7327

Mobile: +82-10-3065-3845

Fax:: +82-2-2258-7859

email: yimds


Received on Tue Jan 17 2017 - 02:42:18 EST

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