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[NMusers] (Senior) M&S scientist/pharmacometrician

From: Andreas Krause <>
Date: Tue, 3 Jan 2017 18:21:14 +0100

Actelion Pharmaceuticals Ltd has an opening for an *M&S
scientist/pharmacometrician* based in the Basel area (Switzerland).

If you are interested and qualified, please apply online:

*​​About The Company*
Actelion Pharmaceuticals Ltd. is a leading biopharmaceutical company
employing over 2,500 dedicated professionals covering all key markets
around the world – including Europe, the US, Japan, China, Russia a=
Mexico. Headquartered in Allschwil near Basel, Switzerland, our functional,
award-winning Actelion Center is a symbol of our innovative spirit and

We are searching for breakthrough medicines for high unmet medical needs
and this inspires and motivates all of us to work towards achieving our
overriding mission: to treat more patients with groundbreaking therapies.

Besides highly competitive compensation and tangible benefits, would you
like to have a noticeable impact and enjoy our culture of innovation, trust
and teamwork? Do you want to grow in a different kind of company with an
enthusiastic, stimulating environment fostered by open communication and a
results-driven approach? Then we welcome your application to join our team
in the role of *(Senior) Modeling and Simulation Scientist /
Pharmacometrician* based in Allschwil.

*Job Responsibilities*

   - Support compounds and projects in clinical development with
   model-based data analysis
   - Support decision making in clinical development by simulation of
   scenarios and studies
   - Contribute to decision making with quantitative assessments of
   efficacy and safety measures of different doses, dosing regimens, and ot=
   relevant variables
   - Identify opportunities for model-based drug development
   - Maintain effective communication with Life Cycle Team, Clinical Team,
   and Clinical Trial Team via the responsible (Senior) Clinical
   Pharmacologist-Coordinate team work within modeling and simulation
   - Ensure high quality contributions to drug development
   - Management of quality and timelines
   - Knowledge of relevant regulatory guidelines and requirements
   - Sustain scientific competence by establishing familiarity with new
   scientific developments
   - Education of colleagues in Clinical Pharmacology and Clinical
   Development about modeling and simulation

*Candidate Requirements*

   - Relevant academic degree (pharmacology, statistics, pharmacometrics)
   with preference for a PhD level of education
   - 3+ years of experience in applying modeling and simulation to drug
   - Good knowledge of drug development and the transition phases
   (preclinical to Phase I, Phase I to II)
   - Experience with relevant software (Monolix, R/S-PLUS,
   ​NONMEM, ​
   Berkeley Madonna)
   - Track record of relevant publications
   - Good interpersonal and communication skills
   - Natural curiosity to learn, phrase questions and share M&S approaches
   with other scientists
   - Scientific mind, interest in research, publications, and presentations

*What Actelion Offers*

   - A competitive salary and generous social benefits
   - The possibility for development and advancement within our dynamic
   - The innovative and stimulating atmosphere of a multicultural

The research facilities are located in Allschwil, Switzerland, a suburb of
Basel on the borders of France and Germany.​

Andreas Krause, PhD
Senior Director Data Management, Modeling and Simulation
Department of Clinical Pharmacology

Actelion Pharmaceuticals Ltd. • Gewerbestrasse 16 • CH-4123=
 Allschwil •
G06.05.W.16.2 •
Address for visitors: Hegenheimermattweg 95


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Received on Tue Jan 03 2017 - 12:21:14 EST

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