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Senior/Principal Scientist (DMPK) – Simcyp (a Cert ara company)

From: Masoud Jamei <masoud.jamei>
Date: Mon, 10 Apr 2017 09:45:00 +0100

Hi All

We have an immediate opening for a Senior/Principal Scientist with a
background in drug metabolism and pharmacokinetics. The candidate should
have familiarity with in vitro-in vivo extrapolation (IVIVE) approaches and
physiologically based pharmacokinetic modelling. Experience working in drug
discovery/development within the Pharmaceutical Industry is desirable.
The successful candidate will join an internationally recognised,
multidisciplinary research team, providing opportunities for further
development of knowledge and skills. In addition to leading a group of
scientists, the successful candidate will undertake novel research projects
to further expand the capabilities of the Simcyp Simulator which requires a
high level of attention to detail, good oral and written communication
skills and the ability to liaise effectively with the Software Development
team. In addition the successful candidate will be expected to provide
on-going customer support, education and training related to the use of the
Simulators, and to act as tutor on the workshop programme. The post does
not include routine laboratory or clinical work.
We offer a unique and exciting mix of academic and commercial environments
which encourage regular attendance at scientific meetings as part of our
continuous education programs.


• PhD (or equivalent experience) in a relevant field with several y=
ears of
practical experience.

• Knowledge of in vitro assays used in drug metabolism and pharmaco=
studies and their application in IVIVE approaches.

• Knowledge of PK/PD properties of small and/or large molecules

• Demonstrable communication skills, as evident by presentation at
scientific meetings, and good interpersonal and organizational skills.

• Track record of publications in peer-reviewed literature.

• Experience of managing other scientists.


• Some understanding of modelling and simulation principles of
physiological and biological systems and parameter estimation techniques.

• Experience in prediction of drug-drug interactions.

• Awareness of R&D process in pharmaceutical companies.

Company Overview:

Simcyp is part of Certara, a company which combines sophisticated research
and development informatics with the power of predictive science
methodologies to span the drug development spectrum and offer pharma a
previously unavailable ‘end-to-end’ solution in the quest f=
or improving
human health. The Simcyp team conducts cutting-edge research and provides
consultancy, knowledge integration tools, algorithms, modelling solutions
and databases (implemented in its globally-recognised Simcyp
Population-based Simulator) for a client base of major blue-chip
pharmaceutical and biotechnology organisations. Simcyp focuses, in
particular, on gathering information required for the modelling and
simulation (M&S) of the individual time-course and fate of drugs. We are on
course to become the global industry standard, consequently, there is a
continuous requirement for high quality people to join us, help in our
expansion and share in our success.

Applications: Please send your CV, covering letter and the names of two
references quoting the job reference/title to simcyp.recruitment

Received on Mon Apr 10 2017 - 04:45:00 EDT

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