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JOB ADVERT: Novartis Pharmacometrics job opportunity

From: Graham, Gordon <gordon.graham>
Date: Tue, 13 Sep 2016 13:56:50 +0000

Dear NMusers,
Novartis is looking for candidates for the position of Director Pharmacomet=
rics Scientist. Please apply through the link below.
Director Pharmacometrics Scientist<

Job ID


Posting Title

Director Pharmacometrics Scientist



Work Location

Cambridge, MA, or East Hanover, NJ, USA

Functional Area

Research & Development

Job Type

Full Time

Job Description

The Director Pharmacometric Scientist will:

* drive pharmacometric strategy at Franchise and/or disease area le=
vel in (early/full) clinical development programs;

* be responsible for driving the design and implementation of pharm=
acometric methodologies that help optimize drug development programs at the=
 Franchise and/or disease area level;

* serve as a consultant to the Franchise level leadership on strate=
gic and regulatory pharmacometrics issues across all stages of development.
The Director Pharmacometric Scientist role requires:

* leading at a global level the planning, execution and delivery of=
 modeling and simulation strategy for multiple indications and/or a disease=
 area (or equivalent) within (early/full) clinical development;

* expert knowledge and domain expertise in certain modeling areas a=
nd also strong therapeutic area expertise in 1-2 disease indications;

* capable of developing collaborative relationships and strategic p=
lans across programs in a therapeutic area;

* responsibility for the design and implementation of pharmacometri=
c methodologies that optimally address the research and development objecti=
ves on the assigned projects;

* setting the strategy for addressing pharmacometric support for re=
gulatory submissions, and directly influences drug development decisions wi=
th internal and external partners;

* identifying the relevant development questions that would benefit=
 from model-based methods and develop modeling plans to deliver meaningful =
and timely results clearly to development teams;

* excellent communication and interpersonal skills and the ability =
to work independently and effectively on interdepartmental project teams;

* good mentoring skills to help other associates and good collabora=
tive skills with other quantitative disciplines including biostatistics.

Minimum requirements

* Ph.D. in pharmacology, biology, engineering, mathematics, statist=
ics, or a field with significant modeling-related content (or equivalent Ph=
.D. / MD) required.

* 8+ years industry experience required.

* Candidates should have requisite expertise in quantitative pharma=
cology, strong hands-on modeling and simulation skills, and demonstrated im=
pact on drug development through quantitative approaches experience.

* Experience with mechanistic PKPD and/or system pharmacology model=
ing is preferred.

* Rich hands-on experience with NONMEM, Monolix, R, Matlab and/or o=
ther modeling and simulation software is required.

* Experience working within clinical project teams and contributing=
 to (early/full-) clinical development strategy with good strategic underst=
anding for applying quantitative analysis at the appropriate time.

* Strong clinical, pharmacological and therapeutic knowledge of at =
least one disease area required.

* Established track record of publications/presentations in pharmac=

* Experience in contributing to scientific improvement/change initi=

* Excellent interpersonal and communication skills

The Novartis Group of Companies are Equal Opportunity Employers and take pr=
ide in maintaining a diverse environment. We do not discriminate in recruit=
ment, hiring, training, promotion or any other employment practices for rea=
sons of race, color, religion, gender, national origin, age, sexual orienta=
tion, marital or veteran status, disability, or any other legally protected=

Gordon Graham
Pharmacometrics I&D Franchise Leader
Novartis Pharma AG
CH-4002 Basel

Phone +41 61 3246253
Mobile +41 79 3959364
Fax +41 61 3241246

Received on Tue Sep 13 2016 - 09:56:50 EDT

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