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Public release of nlmixr, an open source package for population PK and PKPD modelling

From: Wang, Wenping <>
Date: Fri, 21 Oct 2016 17:35:55 +0000

The nlmixr team is very proud to announce the release of nlmixr, an open so=
urce package for population PK and PKPD modelling developed by Wenping Wang=
 and Yuan Xiong. nlmixr builds on Wenping's RxODE package for simulation of=
 nonlinear mixed effect models using ordinary differential equations, by im=
plementing parameter estimation algorithms like nlme, gnlmm and SAEM. nlmix=
r greatly expands the utility of existing packages (like nlme) by providing=
 an efficient and versatile way to specify pharmacometric models and dosing=
 scenarios, with rapid execution due to compilation to C++.

The source is now available at =
along with a vignette, and the models and datasets used in the nlmixr/nlme =
poster to be presented at ACoP (W-66): nlmixr: an open-source package for p=
harmacometric modelling in R on Wednesday, 26 October, 2016, 7:30-9:30 am. =
At this point, nlmixr is still very much in a testing stage and is under li=
vely development. Get in touch, see us at ACoP to discuss ways you could co=
ntribute (Wenping Wang, Yuan Xiong, Justin Wilkins and Rik Schoemaker will =
all be there), or try it out for yourself, and experience the joy of a popu=
lation modelling package within R! A live demo will be possible, so come se=
e Rik if you are interested!

Wenping Wang, PhD
Executive Director, Pharmacometrics
Novartis Pharmaceuticals Corporation
One Health Plaza, East Hanover, NJ 07936-1080, USA
Phone +1 862 7789009; Fax +1 9737818265

Received on Fri Oct 21 2016 - 13:35:55 EDT

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