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Postdoctoral Associate Position at the CPSP (Orlando, FL)

From: Bihorel,Sihem <sihem.bihorel>
Date: Tue, 26 Apr 2016 18:35:25 +0000

Position: Post-doctoral Associate in Pharmacometrics and Systems Pharmacolo=
Department: Center for Pharmacometrics and Systems Pharmacology (CPSP), Col=
lege of Pharmacy, University of Florida
Faculty member: Dr. Sihem Bihorel. MS., PharmD., PhD
Position description: The CPSP in Lake Nona (Orlando, FL) in collaboration =
with Bohringer Ingelheim is offering a two years, full time, post-doctoral =
associate position in clinical pharmacokinetics-pharmacodynamics (PK/PD) an=
d quantitative systems pharmacology (QSP).

This position starts immediately and focuses on the application of QSP with=
 population PK/PD analysis and disease progression modeling in the area of =
exposure-response of novel oral anticoagulants and their management using c=
ombination therapies with reversal agents.
During the two years training at the CPSP, the post-doctoral candidate will=
 have the opportunity to gain a breadth of experience in:

* Population PK/PD and complex mechanism-based modeling of biotechnol=
ogy and small molecule drugs

* Development and qualification of QSP models and bridging these mode=
ls to clinical PK/PD and disease progression models

* Development and evaluation of the advanced numerical and computatio=
nal methods for population PK/PD data analysis

* Development and qualification of novel PK/PD visualization tools fo=
r QSP and population PK/PD analyses.

* Disease progression and risk prediction modeling for patients with =
bleeding disorders

* Report within the project in terms of written reports/publications =
and oral presentations

Qualifications required: An ideal candidate will have a doctoral degree (Ph=
D) in Pharmaceutics, Pharmacometrics (PK/PD), Systems biology/pharmacology,=
 Statistics, applied Mathematics with an interest in pursuing a career in c=
linical pharmacology and/or pharmacometrics & QSP. The candidate must have =
experience with population PK/PD modeling software applications such as NON=
MEM and or Monolix, have programming experience with R and or SAS, is acqua=
inted with MATLAB, have experience in analyzing data describing biologic or=
 PK/PD systems using a non-linear mixed effects modeling approaches, an und=
erstanding of PK and PD theory, particularly as pertaining to biologic agen=
ts will be advantageous.

How to apply: Please send CV, a brief letter of interest, and the names and=
 email addresses of three referees to Dr. Sihem Bihorel, MS., PharmD., PhD =
via e-mail to sihem.bihorel
CPSP Overview: The CPSP ( is located in the U=
niversity of Florida Academic & Research Center at the Lake Nona Medical Ci=
ty about 5 miles southeast of the Orlando International Airport. The CPSP p=
rovides an academic home to a multidisciplinary and integrative, quantitati=
ve clinical pharmacology program in drug development and regulatory science=
. Lake Nona Medical City ( is a landm=
ark for Orlando and a premier location for medical care, research and educa=
tion. It is anchored by University of Central Florida Medical School, the S=
anford-Burnham Medical Research Institute, the newest VA Medical Center in =
the country, the Nemours Children's Hospital, and the University of Florida=
 Academic and Research Center.

Received on Tue Apr 26 2016 - 14:35:25 EDT

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