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[NMusers] mu coding for variability in SD

From: Pavel Belo <nonmem_at_optonline.net>
Date: Fri, 20 Nov 2015 15:30:54 -0500 (EST)


Hello The NONMEM Professionals,
 
The model requires SAEM.  Is mu coding useful when each subject h=
as to
have different SD (SDi=SD0*exp(etai))?
 
It may look something like
 
MU_8  =THETA(8) 
SD      = DEXP(MU_8 +ETA(8))
 
$THETA (0.00001,0.0413,50)      ;SD1
$THETA (0.001 FIX)         =
          ;SD2
 
GRD=TG(1-9)    ;(instead of   GRD=TG(1-7):TS(8=
-9))
 
Thanks!
Pavel 






Received on Fri Nov 20 2015 - 15:30:54 EST

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