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[NMusers] Openings for Postdoc Positions at the University of Florida, Orlando in Pharmacometrics and Systems Pharmacology

From: Mirjam Trame <>
Date: Tue, 5 May 2015 12:17:06 -0400

*Postdoctoral Research Associate in Pharmacometrics and Systems

*Center for Pharmacometrics and System Pharmacology*

*Department of Pharmaceutics, College of Pharmacy University of Florida*

*Orlando (Lake Nona), Florida*

*Job Function:* Postdoctoral Research Associate Positions
in Pharmacometrics, PBPK modeling, Systems Biology/Pharmacology

*Entry Level: * N/A

*Setting:* College/University/Medical City Campu=

*Location:* Orlando (Lake Nona), Florida, United

*Job Type: * Full-Time

*Minimum Education:* Ph.D. or equivalent degree in quantitative
sciences including Pharmacometrics, Engineering, Statistics, Mathematics
and Systems Biology/Pharmacology

*Fellowship Description*

The mission of the Center for Pharmacometrics and System Pharmacology
(CPSP) at the University of Florida (UF) is to develop new quantitative
tools and mechanistic approaches to evaluate and predict the efficacy and
safety of medicines. The CPSP has several two year fellowships available
for scientists who intend to further their training for a career in drug
development, academia or regulatory science.

The successful applicants will have access to clinical trial data in order
to learn how to apply and become proficient in using population-based PK/PD
modeling, PBPK, Systems Biology/Pharmacology and computer simulation
approaches to solve drug development and regulatory problems such as
optimal dosing and biomarker qualification. Depending on the availability
of projects and interests of the applicant, he or she will also learn how
to effectively use disease progression models and physiologically based
PK/PD models to design clinical trials, understand the pharmacological
mechanisms of drug action, explore covariate effects on PK and PD and
determine the influence of genetic factors on drug dosing. The fellow will
have the opportunity to participate in systems pharmacology research under
the direction of a CPSP faculty to identify the mechanistic basis of drug
adverse drug events arising out of drug development programs, FDA safety
alerts or clinical practice.

Postdoctoral research associates will engage in a combination of duties
that will include research projects, graduate student mentoring, grant
writing and classroom teaching experiences. Fellows will also gain
experience outside the University of Florida through industry or FDA
internships or off-site participation in research with our Orlando partners
including the Sanford Burnham Medical Research Institute (SBMRI), Nemours
Children Hospital, and SBMRI-Florida Hospital Translational Research
Institute. It is expected that fellows attend and present at professional
meetings, participate in workshops and seminars and prepare at least 3-4
peer-reviewed publications to build a foundation for personal career
achievements. In addition to the scientific and clinical duties, fellows
are given the opportunity to grow their “soft skills”, such=
 as oral
communication, presentation skills and working on multi-disciplinary teams.

*Job Qualifications*

Preferred qualifications for the position are a doctoral (Ph.D. or
equivalent) degree in quantitative sciences including Pharmacometrics,
Engineering, Statistics, Mathematics and Systems Biology as well as
knowledge of, or experience in, therapeutics in one or more disease areas
with an interest in pursuing a career in Pharmacometrics and/or Systems
Pharmacology. The ideal candidate should possess strong programming
skills, excellent written and verbal communication, good organizational
abilities, and team work. A background and understanding of basic
pharmacology, pharmacometrics and/or systems biology/pharmacology is
preferred as is hands-on knowledge in using software platforms such as
NONMEM, MATLAB, R, SAS, PK-Sim, GastroPlus, SimCYP or other
software/scripting languages is required. The candidate must be
self-directed and self-motivated.

*Center for Pharmacometrics and System Pharmacology (CPSP) Overview*

The CPSP is located in the University of Florida Academic & Research Center
at the Lake Nona Medical City about 5 miles southeast of the Orlando
International Airport. The CPSP provides an academic home to a
multidisciplinary and integrative, quantitative clinical pharmacology
program in drug development and regulatory science. Lake Nona Medical City
is a landmark for Orlando and a premier location for medical care, research
and education. It is anchored by University of Central Florida Medical
School, the Sanford-Burnham Medical Research Institute, the newest VA
Medical Center in the country, the Nemours Children's Hospital, and
University of Florida Academic & Research Center. In addition to the
pharmaceutical industry and the FDA, CPSP will also provide the opportunity
for hard-working and self-motivated candidates to work collaboratively with
a multidisciplinary group of scientists from other institutes and hospitals
in the Orlando area.

*To Apply*

Please send curriculum vitae and contact information for three references t=
 Dr. Lawrence J. Lesko,, 6550 Sanger Road Orlando, FL


*Mirjam Trame, Pharm.D., Ph.D.*

Assistant Professor

Center for Pharmacometrics & Systems Pharmacology

Department of Pharmaceutics

University of Florida

6550 Sanger Road, Office 471

Orlando, FL 32827

Phone: +1 (407) 313 7052

Fax: +1 (407) 313 7030

Cell: +1 (407) 764 0070


Received on Tue May 05 2015 - 12:17:06 EDT

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