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[NMusers] PFIM Interface 4.0 is released!

From: Emmanuelle Comets <>
Date: Tue, 09 Jun 2015 16:45:33 +0200

                Dear Nonmem users,

The PFIM group ( <>), would like to in=
you that we have released PFIM Interface 4.0, the new version of the PFIM
graphical user Interface.

It can easily be downloaded on the internet site http://www.pfim.biostat.=

PFIM Interface 4.0 incorporates several new features based on the R scrip=
program of PFIM 4.0 and they are listed below:

·For population designs, optimisation can be performed with fixed param=
eters or
fixed sampling times.

·The Fisher information matrix obtained after evaluation or optimisatio=
n can be
saved in a file.

·Additional features for Bayesian designs are now available. The Bayesi=
an Fisher
information matrix has been implemented. Design for maximum a posteriori
estimation of individual parameters can be evaluated or optimised and the
predicted shrinkage is also reported.

·A new way has been added to specify user-defined models through an R f=

·It is now possible to visualise the graphs of the model and the sensit=
functions without performing evaluation or optimisation.

Together with the new Interface we also release the User Guide for PFIM
Interface 4.0. It includes detailed descriptions of all the features avai=
in PFIM Interface, from the basics to the most recent and advanced ones. =
“Use” section will take you through the new Interface and a series of=
covering most possible features, is also provided. The User Guide of PFIM
Interface 4.0 goes automatically inside the directory of PFIM Interface 4=
.0, but
it can also be separately downloaded in the Documentation section at the =
internet site

Best regards,

                on behalf of the PFIM group

Giulia Lestini
PhD student
IAME UMR-S 1137, INSERM and Université Paris Diderot
16 rue Henri Huchard
75018 Paris, France
tel: 33 (0) 1 57 27 75 40
email :

Received on Tue Jun 09 2015 - 10:45:33 EDT

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