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Re: Covariate modelling question

From: Kajsa Harling <kajsa.harling>
Date: Thu, 26 Feb 2015 11:55:42 +0100
I have looked at the output now, and am writing the answer to the mailing list in case more people are interested.

In the two different scm runs you get slightly different ofv values, and the small differences lead to different models being selected in the two runs. So why are the ofv:s different? One possible reason is that you used the retries option in PsN (automatic perturbation of initial estimates when a run is not successful) which will give different initial estimates depending on the random seed. You can check the settings of all PsN options, including the ones set by default, in the version_and_option_info.txt file in the top level of the scm run directory.

Best regards,
Kajsa

On 02/26/2015 11:28 AM, Kajsa Harling wrote:
Dear Fiona,

This sounds like a PsN question, but it is impossible to answer without the example output. The mailing list does not accept long messages or attachments, so I suggest you send the original email with all output directly to me (On 02/26/2015 11:00 AM, Fiona Vanobberghen wrote:
--
Fiona Vanobberghen (née Ewings), PhD
Swiss Tropical and Public Health Institute
Socinstrasse 57, 4051, Basel, Switzerland
Tel: +41 61 284 87 41



-- 
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Kajsa Harling, PhD
System Developer
Department of Pharmaceutical Biosciences
Uppsala University

http://www.farmbio.uu.se/research/researchgroups/pharmacometrics/
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-- 
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Kajsa Harling, PhD
System Developer
Department of Pharmaceutical Biosciences
Uppsala University

http://www.farmbio.uu.se/research/researchgroups/pharmacometrics/
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Received on Thu Feb 26 2015 - 05:55:42 EST

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