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Re: [NMusers] setup of parallel processing and supporting software - help wanted

From: Mark Sale <msale_at_nuventra.com>
Date: Tue, 8 Dec 2015 23:04:14 +0000

WRT bootstrap, it makes much more sense to simply bootstrap the many nonmem=
 runs (start 8 NONMEM runs at at time, rather than 1 run parallelized to 8 =
cores).

So, no, don't use parallel NONMEM for bootstrap, run multiple bootstrap sam=
ples at the same time.



Mark


Mark Sale M.D.
Vice President, Modeling and Simulation
Nuventra, Inc. (tm)
2525 Meridian Parkway, Suite 280
Research Triangle Park, NC 27713
Office (919)-973-0383
msale_at_nuventra.com<msale_at_kinetigen.com>
www.nuventra.com<http://www.nuventra.com>



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________________________________
From: owner-nmusers_at_globomaxnm.com <owner-nmusers_at_globomaxnm.com> on behalf=
 of Pavel Belo <nonmem_at_optonline.net>
Sent: Tuesday, December 8, 2015 4:54 PM
To: nmusers_at_globomaxnm.com
Subject: [NMusers] setup of parallel processing and supporting software - h=
elp wanted

Hello The Team,

We hear different opinions about effectiveness of parallel processing with =
NONMEM from very helpful to less helpful. It can be task dependent. How =
useful is it in phase 3 for basic and covariate models, as well as for boot=
strapping?

We reached a non-exploratory (production) point when popPK is on a critical=
 path and sophisticated but slow home-made utilities may be insufficient. =
Are there efficient/quick companies/institutions, which setup parallel proc=
essing, supporting software and, possibly, some other utilities (cloud comp=
uting, ...)? A group which used to helped us a while ago disappeared somew=
here...

Thanks,
Pavel

Received on Tue Dec 08 2015 - 18:04:14 EST

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