NONMEM Users Network Archive

Hosted by Cognigen

PsN Stop: Out of memory.

From: Xinting Wang <wxinting1986>
Date: Mon, 19 May 2014 23:24:14 +0800

Dear all,

I am conducting a scm search of covariates using PsN. The model uses ADVAN6
with FO estimation method. Due to the complexity of the model, it crashes
after 13 rounds of running with an error message saying:

out of memory!

The scm uses a parallel processing of 5 CPU cores. At the beginning of the
model we stated $SIZE as below:

$SIZES LIM6=3224 LTH=70 LVR=20 NO=1000

The base model has 15 thetas and 8 ETAs. After 13 rounds of scm, the model
has 38 thetas, which is well below LTH. After checking the last run, all
the NONMEM RUNS were finished in the m1 folder. I was wondering if anybody
has encountered such a problem before? Is this because of inappropriate
resource allocation, or because of the memory shortage? Actually, I am not
even sure whether this is because of error in PsN, or error in the NONMEM

Some other details of the model:
1. scm file investigates effect of 5 covariates on 8 parameters (5*8);
2. NONMEM is ver 7.2.

Many thanks for your kind help.

Best Regards


Received on Mon May 19 2014 - 11:24:14 EDT

The NONMEM Users Network is maintained by ICON plc. Requests to subscribe to the network should be sent to:

Once subscribed, you may contribute to the discussion by emailing: