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Pharmacometrics Network Benelux - Third meeting announcement (REMINDER)

From: Brochot, Anne [JRDBE] <ABROCHOT>
Date: Sun, 17 Nov 2013 15:26:26 +0000

Dear Colleagues,
 It is a pleasure to invite you for the third meeting of Pharmacometrics Ne=
twork Benelux. There are still some spaces available.
 Please mark the following date and time in your agenda :
 When: Thursday, November 28th - 12:30 - 18:00
Where: Astellas , Advagraf & Prograf rooms, Mirai House, Sylviusweg 62, 233=
3 BE Leiden, The Netherlands
Agenda theme: Modeling and simulation in pediatric drug development

You can register by sending an e-mail to Petra Bitter by Monday November 25=
E-mail: petra.bitter
is no registration fee, but registration is required for participation.

12.30 -13.25 Welcome coffee, tea and sandwiches
13.25-13.30 Introduction
13.30-14.00 Everybody wants to get the dose right!...right? Edwin Spaa=
ns, PharmD, Department of Intensive Care, ErasmusMC Sophia Children's Hos=
pital and Kinesis Pharma BV
14.00-14.25 Predicting the efficacy of the Nanobody® ALX-0681 in ped=
iatric patients. Massimiliano Germani, PhD, Ablynx
14.25-14.50 Scaling PK to estimate first dose in children. Ashley Stro=
ugo, PhD, Astellas
14.50-15.15 Model-based dosing rationale for darunavir when co-adminis=
tered with low-dose ritonavir in pediatric HIV-1 infected patients. Anne Br=
ochot, MSc, Janssen Pharmaceutica
15.15-15.45 Coffee/Tea break
15.45-17.00 Work in progress presentations and discussions
- Pharmacokinetic modeling and dose optimization of the polyclonal antibody=
 Thymoglobulin in pediatric patients in stem cell transplantation setting. =
Rick Admiraal, MD; Department of Pediatric Immunology, University Medical C=
enter Utrecht; Division of Pharmacology, LACDR, Leiden University; Departme=
nt of Pediatrics, Leiden University Medical Center, Leiden
- Challenges in the prediction of dosages for new drugs in pediatric patien=
ts: the potential and limitations of application of semi-physiological mode=
ls. Prof Catherijne AJ Knibbe, PharmD PhD; Division of Pharmacology, LACDR=
, Leiden University and St Antonius Hospital Nieuwegein
-Quantitative in vitro-based pediatric PBPK predictions of tramadol: how cl=
ose can we get? Huybrecht T'Jollyn, PhD candidate, Laboratory of Medical Bi=
ochemistry and Clinical Analysis, Department of Bioanalysis, Faculty of Pha=
rmaceutical Sciences, Ghent University
17.00-17.15 Conclusion
17.15-18.00 Drinks and snacks
There will be a security check when arriving at Astellas (ID required) and =
participant will receive a badge. Also, the parking capacity is limited so =
we encourage you to car pool or to use public transportation (Astellas prem=
ises are located 15 min walking from Leiden Central Station).

Travelling options to Astellas Mirai House
Sylviusweg 62
2333 BE Leiden
The Netherlands
Tel: +31 (0)71 545 5745

By car
From the direction of The Hague (N44, A44):
Please follow the N44 (later the A44) from The Hague until exit 8 (Leiden, =
Noordwijk, Katwijk) and at the end of the exit you turn to the right. Then =
you follow the signs " Bio Science Park", this is the first possible turn t=
o the left (second traffic light). After this you take the third possible t=
urn to the right. Astellas is the first building on your left.
From the direction of Amsterdam (A4, A44):
Follow the A4 and then the A44 in the direction of Leiden-West. You follow =
the A44 until exit 8 (Leiden, Noordwijk, Katwijk N206). After te exit you t=
urn left under the viaduct. Then you follow the signs "Bio Science Park", t=
his is the first possible turn to the left (second traffic light). After th=
is you take the third possible turn to the right. Astellas is the first bui=
lding on your left.
If you travel with a navigation system, you will have to enter the street n=
ame Einsteinweg 1 in Leiden, because the system can't find the Sylviusweg. =
After that you will have to follow the last instructions as mentioned above=
 By public transport
The train station Leiden Central is within walking distance of our new buil=
ding (15 minutes). There are also two bus stops with frequent services to L=
eiden Central Station within 250 meters of Mirai House. Please check http:=

We hope to see you in Leiden on November 28!

Anne Brochot
Eugène Cox
Rik de Greef
Charlotte van Kesteren
Thomas Kerbusch
Catherijne Knibbe
Ron Mathôt
Stefaan Rossenu
Jan-Stefan Van der Walt
An Vermeulen

On Pharmacometrics Network Benelux: the initiative aims to connect pharmaco=
metricians in the Benelux (Belgium, Netherlands, Luxembourg). The intention=
 is to create an informal platform for the pharmacometric community in this=
 region of the world (in industry, academia, hospital pharmacies as well as=
 regulatory bodies), with the goal to promote professional and scientific a=
wareness and interactions.

Stay tuned on our latest activity by joining our group on LinkedIn.

Received on Sun Nov 17 2013 - 10:26:26 EST

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