NONMEM Users Network Archive

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Re: Sensitive analysis

From: Norman Z <freecg>
Date: Mon, 20 Feb 2012 17:31:31 -0500

Hi NMUsers,

A lot of very constructive suggestions were provided since I posted my
question. I sincerely appreciate everybody for your help.

Norman

On Mon, Feb 20, 2012 at 5:22 AM, Lewis, Joanna <joanna.lewis

> Dear Norman,
>
> If you are an R user, I have had some success using the FME package for
> this sort of sensitivity analysis:
>
> http://cran.r-project.org/web/packages/FME/index.html
> www.jstatsoft.org/v33/i03/paper
>
> Hope that might be of some help.
>
> Joanna
>
> Joanna Lewis
> PhD student
> UCL Institute of Child Health,
> 30 Guilford Street,
> London WC1N 1EH
> 0207 905 2307
>
> From: Norman Z <freecg
> Date: Sat, 18 Feb 2012 21:16:15 -0500
>
> To: <nmusers
> Subject: [NMusers] Sensitive analysis
>
> Hello everyone,
>
>
>
> I am doing some sensitive analysis for the final model parameters, where I
> want to increase/decrease the parameter estimation by 10% and look at its
> impact on the model prediction.
>
> My model is built in NONMEM 7. And I have WFN and PsN installed. I wonder
> if anybody could suggest how to automatic carry out sensitive analysis. Is
> PsN or WFN capable of doing so? Of course, the last resort would be to
> manually change the parameters and run the model.
>
>
>
> Thanks for your help.
>
>
>
> Norman
>
>
>

Received on Mon Feb 20 2012 - 17:31:31 EST

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