NONMEM Users Network Archive

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RE: repetitive parameter estimation

From: Bill Bachman <bachmanw>
Date: Mon, 21 Mar 2011 15:16:38 -0400

See the documentation for $DATA. Set up multiple problems within a single
control file. Use the RECORDS= option to select the number of data records
for 50 patients, use the NOREWIND option so that for each problem, the data
for the next 50 patients.

  _____

From: owner-nmusers
Behalf Of kehua wu
Sent: Monday, March 21, 2011 2:55 PM
To: nmusers
Subject: [NMusers] repetitive parameter estimation


Hi,

We have a data file with 250,000 simulated patients, and we want to estimate
a parameter in NONMEM using a different set of 50 patients at a time (5,000
replicates, but not bootstrapping). Is there an easy way that anybody knows
to automatically repeat the parameter estimation while substituting the new
data each time?

Thanks,

Kehua

Received on Mon Mar 21 2011 - 15:16:38 EDT

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