Re: [NMusers] Log Transformed AST

From: Duy Tran <duytran16_at_gmail.com>
Date: Mon, 22 Jul 2019 16:49:32 -0700

If you desire to log transform by base 10 instead of e, use *LOG10* in
NONMEM instead of *LOG*

On Mon, Jul 22, 2019 at 4:43 PM Ranita Kirubakaran <
r.kirubakaran_at_unsw.edu.au> wrote:

> Dear all,
>
> I am a PhD student working on NONMEM as a new user. I am working on
> external evaluation of some of the selected published population PK model=
s.
> While trying to implement one of the models in NONMEM, I realised that if
> I code log-transformed aspartate aminotransferase (LAST) as LAST =
> LOG(AST), the sdtab output is giving me the In(AST) value instead of a
> LOG(AST) value. Was wondering if NONMEM interprets all Log (x) as Log e (=
x)
> instead of Log 10 (x)?
>
> Thank you.
>
> Best Regards,
>
> *Ranita Kirubakaran*
>
> *PhD Candidate*
>
>
> *Ranita Kirubakaran*
>
>
>
> *PhD Candidate*
> St Vincent’s Clinical School | *UNSW Sydney*
> Department of Clinical Pharmacology and Toxicology
> Therapeutics Centre | Level 2 Xavier Building
> *St Vincent’s Hospital*
> 390 Victoria Street | Darlinghurst NSW 2010 | Australia
>
> *E* r.kirubakaran_at_student.unsw.edu.au | *P* +61 (2) 8382 2199 | *F* +61
> (2) 8382 2724
>
>


Received on Mon Jul 22 2019 - 19:49:32 EDT

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