[NMusers] Log Transformed AST

From: Ranita Kirubakaran <r.kirubakaran_at_unsw.edu.au>
Date: Mon, 22 Jul 2019 23:37:14 +0000

Dear all,

I am a PhD student working on NONMEM as a new user. I am working on externa=
l evaluation of some of the selected published population PK models. While =
trying to implement one of the models in NONMEM, I realised that if I code =
log-transformed aspartate aminotransferase (LAST) as LAST = LOG(AST), the=
 sdtab output is giving me the In(AST) value instead of a LOG(AST) value. =
Was wondering if NONMEM interprets all Log (x) as Log e (x) instead of Log =
10 (x)?

Thank you.

Best Regards,

Ranita Kirubakaran

PhD Candidate

Ranita Kirubakaran

PhD Candidate
St Vincentís Clinical School | UNSW Sydney
Department of Clinical Pharmacology and Toxicology
Therapeutics Centre | Level 2 Xavier Building
St Vincentís Hospital
390 Victoria Street | Darlinghurst NSW 2010 | Australia

E r.kirubakaran_at_student.unsw.edu.au<mailto:r.kirubakaran_at_student.unsw.edu.a=
u> | P +61 (2) 8382 2199 | F +61 (2) 8382 2724

Received on Mon Jul 22 2019 - 19:37:14 EDT

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