[NMusers] Principal Scientist, Pharmacometrics, MA

From: Brenda Roseberry <broseberry_at_cartermackay.com>
Date: Wed, 14 Nov 2018 18:05:58 +0000

My client is looking for a Principal scientist level modeler to work on pro=
ject teams and perform various quantitative approaches to drug development.=
 If interested please email me at broseberry_at_cartermackay.com<mailto:broseb=
erry_at_cartermackay.com>

Principal Scientist, modeling/simulation-location: MA
The successful candidate will support Discovery and Early Development progr=
ams as the modeling and simulation expert from DMPK. The overall goal is to=
 support prediction of optimal dosing regimens for both biologics and small=
 molecules and integrate findings and modeling efforts across Discovery and=
 Development, as well as integrate findings and efforts with Clinical Pharm=
acology activities. Close interaction with DMPK scientists at early stages =
should be anticipated, to provide guidance on supporting in vivo and in vit=
ro studies needed to perform modeling.
Qualifications:

  * A Ph.D. degree with 6+ years, or a M.S. with 10+ years, in pharmacoki=
netics, clinical pharmacology or related disciplines.
  * The position requires in-depth knowledge of PKPD (direct and indirect=
) modeling techniques and tools (e.g. WinNonLin/Phoenix, R) as well as phar=
macokinetics, compartmental and non-compartmental analysis of small molecul=
es and biologics with the goals of predicting an optimal dose regimen.
  * Experience with long-acting injectable formulations and pro-drug PK m=
odeling is a strong plus.
  * Expertise and experience in biologics for Oncology is considered a st=
rong plus. Expertise in PBPK methods would be a strong plus.
  * Strong organization, multi-tasking and communication skills are key a=
ttributes of the successful candidate who should be able to explain results=
 and assumptions underlying modeling efforts to project teams.
  * Integration with Clinical Pharmacology is a core expectation for the =
role. Individuals with first-author, peer-reviewed publications and/or pres=
entations will be strong candidates for this role.



[cid:1.1213385771_at_web31815.mail.mud.yahoo.com]
Brenda Roseberry
   Division Manager-Scientific
   Preclinical/Clinical--PK, Pharmacology, Pharmacometrics, Biomarkers
    720-328-9526 - Office
    315-415-4353 - Mobile
    720-475-1176 - Fax
   [cid:image001.png_at_01CBC1F8.25033B10] <http://www.linkedin.com/profile/vi=
ew?id=19937880&authType=name&authToken=b5d_>





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Received on Wed Nov 14 2018 - 13:05:58 EST

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