RE: [NMusers] Error with SAEM and LIKE Option

From: Sadler, Brian <Brian.Sadler_at_iconplc.com>
Date: Fri, 13 Jan 2017 15:34:15 +0000

Hi Varun,

You might try explicitly using “NOINTERACTION” with SAEM and IMP.

Cheers… Brian

From: owner-nmusers_at_globomaxnm.com [mailto:owner-nmusers_at_globomaxnm.com] On Behalf Of varun goel
Sent: Friday, January 13, 2017 9:55 AM
To: nmusers_at_globomaxnm.com
Subject: [NMusers] Error with SAEM and LIKE Option

Dear All,
I get error while using SAEM estimation method for repeated time to event model. But, the same model runs well with LAPLACE. Could you suggest what I am missing below.

This $EST runs well
$ESTIMATION MAXEVAL=999 METHOD=COND LAPLACE LIKE PRINT=1

Following $EST method fails with the following error
$EST METHOD=SAEM LAP LIKE NBURN=1000 NITER=1000 PRINT=200 IACCEPT=0.2 CTYPE=3
CINTERVAL=10
$EST METHOD=IMP LAPLACE CTYPE=3 CINTERVAL=1 NITER=300
IACCEPT=0.2 DF=6 SEED=123

Error
(WARNING 121) INTERACTION IS IMPLIED WITH EM/BAYES ESTIMATION METHODS

AN ERROR WAS FOUND IN THE CONTROL STATEMENTS.

545 $ESTIM: "INTERACTION" CANNOT BE USED WITH "LIKE" OR "-2LL".

Varun
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Received on Fri Jan 13 2017 - 10:34:15 EST

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