Re: [NMusers] $PRIOR with normal for OMEGA?
Not sure about this but how about estimating THETAS scaling fix OMEGAs (e.g.=
CL = THETA(1)*EXP(THETA(2)*ETA(1)) ; $OMEGA 1 fix)? Then you can implemen=
t the prior in the same way for random effect parameters as you do for fixed=
Ps. Probably not be compatible with MU-parameterization.
Martin Bergstrand, Ph.D.
+46(0)709 994 396
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752 37 Uppsala, Sweden
Skickat från min iPhone
11 nov. 2016 kl. 04:57 skrev Mark Sale <msale_at_nuventra.com>:
> Is it possible to use a normal prior for OMEGA? The default is inverse Wis=
hart, but I'd be interested in using Normal (insuring that it is positive de=
finite) Any ideas?
> Mark Sale M.D.
> Vice President, Modeling and Simulation
> Nuventra Pharma Sciences, Inc.
> 2525 Meridian Parkway, Suite 280
> Durham, NC 27713
> Phone (919)-973-0383
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Received on Fri Nov 11 2016 - 02:32:05 EST
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