[NMusers] Sr Pharmacometrician position at Vertex

From: Ulf Bredberg <Ulf_Bredberg_at_vrtx.com>
Date: Tue, 12 Apr 2016 18:49:04 +0000

Senior Pharmacometrican position at Vertex Pharmaceuticals, Boston

Modeling & Simulation (M&S) methodologies plays an increasingly important r=
ole in the development of new drugs within Vertex Pharmaceuticals and our g=
oal is to fully implement Model based principles to inform drug development=
 program with respect to translational modeling, clinical trial design, PoP=
PK and PKPD , dose selection etc, and improve critical decision making.
We are now seeking a Senior Pharmacometrician to our Modeling & Simulations=
 (M&S) group to help us achieve this vision.
The successful candidate will provide Modeling&Simulation expertise in one =
or several projects in close collaboration with colleagues in Clinical Phar=
macology, Biostatistics, Preclinical Research and other colleagues within t=
he R&D organization.

Key responsibilities


* Support project teams with state-of-the-art modeling expertise co=
vering all phases of Drug development (Translational stage- Ph III/IV)

* Perform Population PK, PKPD-analyses, Clinical trial simulations=
 and other model based analyses on a regular basis

* Deliver high quality M&S presentations and reports

* Contribute to the continuous development of our M&S Department ca=
pabilities (tools, methods etc)

Required Qualifications

* PhD in PKPD, Clinical pharmacology, or other quantitative discip=
line with an emphasis on M&S and Pharmacometric methodologies

* 3-5 yrs post PhD hands-on experience in the application of M&S a=
nd Pharmacometric methodologies within the context of drug development.

* Excellent hands-on skills in Non-linear Mixed effect modeling and=
 other modeling methodologies using NonMem, PsN, R, Phoenix, and other sim=
ilar tools

* A solid understanding of fundamental pharmacokinetic, quantitativ=
e pharmacology (PKPD), and Biostatistical principles.

* Excellent collaborative, verbal and written communication skills

Desirable qualifications


* Experience from Pharmacometric analyses in Pulmonary diseases, On=
cology or Neurological disorders.



* Experience from the application of System pharmacology in a drug =
development context

If you are interested in applying to the position, please go this link http=
s://sjobs.brassring.com/TGWebHost/home.aspx?partnerid=25119&siteid=5134=
 Click search openings, under keyword type in 7930BR




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Received on Tue Apr 12 2016 - 14:49:04 EDT

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