Re: [NMusers] $SIZES failed

From: Nick Holford <n.holford_at_auckland.ac.nz>
Date: Thu, 18 Jun 2015 07:27:48 +0200

Hi,

Sam is using WFN.

WFN adds -prdefault by default to the command line. This speeds up
typical use of NONMEM by avoiding recompilation.
The default behaviour is changed by unsetting the environment variable
args7:

set args7=

This will then allow WFN users to use $SIZES.

Best wishes,

Nick

On 18/06/2015 12:42 a.m., Sam Liao wrote:
> Dear Robert,
> I did not have –prdefault anywhere in my command.
>
> Best regards,
> Sam Liao
> Pharmax Research Inc.
> 14 Upland,
> Irvine, CA 92602
> Phone: 201-9882043
> efax: 720-2946783
> www.pharmaxresearch.com
>
> On 6/17/2015 2:21 PM, Bauer, Robert wrote:
>>
>> Do not add –prdefault on your command line.
>>
>> Robert J. Bauer, Ph.D.
>>
>> Vice President, Pharmacometrics R&D
>>
>> ICON Early Phase
>>
>> Office: (215) 616-6428
>>
>> Mobile: (925) 286-0769
>>
>> Robert.Bauer_at_iconplc.com <mailto:Robert.Bauer_at_iconplc.com>
>>
>> www.iconplc.com <http://www.iconplc.com>
>>
>> *From:*owner-nmusers_at_globomaxnm.com
>> [mailto:owner-nmusers_at_globomaxnm.com] *On Behalf Of *Sam Liao
>> *Sent:* Wednesday, June 17, 2015 1:36 PM
>> *To:* nmusers_at_globomaxnm.com
>> *Subject:* [NMusers] $SIZES failed
>>
>> Hi,
>> My PK model has 42 theta and 35 omega exceeding the default limits.
>> When I used $SIZE to change these size in my control file, I still get
>> the error msg from nmtran.exe
>> "MAY NOT USE -prdefault: LVR IN SIZES.f90 WOULD NEED TO BE INCREASED
>> TO 35"
>>
>> Is there way to get around this problem? Somehow, the $SIZE statement in
>> the control stream was ignored.
>>
>> --
>> Sam Liao
>> Pharmax Research Inc.
>> 14 Upland,
>> Irvine, CA 92602
>> Phone: 201-9882043
>> efax: 720-2946783
>> www.pharmaxresearch.com <http://www.pharmaxresearch.com>
>>
>>
>>
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>>
>
>
> --
> Sam Liao
> Pharmax Research Inc.
> 14 Upland,
> Irvine, CA 92602
> Phone: 201-9882043
> efax: 720-2946783
> www.pharmaxresearch.com

--
Nick Holford, Professor Clinical Pharmacology
Dept Pharmacology & Clinical Pharmacology, Bldg 503 Room 302A
University of Auckland,85 Park Rd,Private Bag 92019,Auckland,New Zealand
office:+64(9)923-6730 mobile:NZ+64(21)46 23 53 FR+33(7)80 48 55 50
email: n.holford_at_auckland.ac.nz
http://holford.fmhs.auckland.ac.nz/

Holford SD, Allegaert K, Anderson BJ, Kukanich B, Sousa AB, Steinman A, Pypendop, B., Mehvar, R., Giorgi, M., Holford,N.H.G. Parent-metabolite pharmacokinetic models - tests of assumptions and predictions. Journal of Pharmacology & Clinical Toxicology. 2014;2(2):1023-34.
Holford N. Clinical pharmacology = disease progression + drug action. Br J Clin Pharmacol. 2015;79(1):18-27.

Received on Thu Jun 18 2015 - 01:27:48 EDT

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