[NMusers] Openings for Postdoc Positions at the University of Florida, Orlando

From: Mirjam Trame <mirjam.trame_at_gmail.com>
Date: Wed, 10 Dec 2014 11:10:30 -0500

*Postdoctoral Research Associate in Pharmacometrics and Systems

*Center for Pharmacometrics and System Pharmacology*

*Department of Pharmaceutics, College of Pharmacy University of Florida*

*Orlando (Lake Nona), Florida*

*Job Function:* Postdoctoral Research Associate
Positions in Pharmacometrics, PBPK modeling, Systems Pharmacology and
Analytical (LCMS) Method Development

*Entry Level: * N/A

*Setting:* College/University/Medical City

*Location:* Orlando (Lake Nona), Florida, United

*Job Type: * Full-Time

*Minimum Education:* Ph.D. or equivalent degree in quantitative
sciences including Engineering, Statistics, Mathematics and Systems Biology

*Fellowship Description *

The mission of the Center for Pharmacometrics and System Pharmacology
(CPSP) at the University of Florida (UF) is to develop new quantitative
tools and mechanistic approaches to evaluate and predict the efficacy and
safety of medicines. The CPSP has several two year fellowships available
for scientists who intend to further their training for a career in drug
development, academia or regulatory science.

The successful applicants will have access to clinical trial data in order
to learn how to apply and become proficient in using population-based PK/PD
and PBPK modeling and computer simulation approaches to solve drug
development and regulatory problems such as optimal dosing and biomarker
qualification. Depending on the availability of projects and interests of
the applicant, he or she will also learn how to effectively use disease
progression models and physiologically based PK/PD models to design
clinical trials, understand the pharmacological mechanisms of drug action,
explore covariate effects on PK and PD and determine the influence of
genetic factors on drug dosing. The fellow will have the opportunity to
participate in systems pharmacology research under the direction of a CPSP
faculty to identify the mechanistic basis of drug adverse drug events
arising out of drug development programs, FDA safety alerts or clinical
practice. Some of the projects will be coupled with LCMS biomarker
analysis in which the candidate would be enrolled in LCMS method
development for metabolomic studies.

Postdoctoral research associates will engage in a combination of duties
that will include research projects, graduate student mentoring, grant
writing and classroom teaching experiences. Fellows will also gain
experience outside the University of Florida through industry or FDA
internships or off-site participation in research with our Orlando partners
including the Sanford Burnham Medical Research Institute (SBMRI), Nemours
Children Hospital, and SBMRI-Florida Hospital Translational Research
Institute. It is expected that fellows attend and present at professional
meetings, participate in workshops and seminars and prepare at least 3-4
peer-reviewed publications to build a foundation for personal career
achievements. In addition to the scientific and clinical duties, fellows
are given the opportunity to grow their “soft skills”, such=
 as oral
communication, presentation skills and working on multi-disciplinary teams.

*Job Qualifications*

Preferred qualifications for the position are a doctoral (Ph.D. or
equivalent) degree in quantitative sciences including Engineering,
Statistics, Mathematics and Systems Biology as well as knowledge of, or
experience in, therapeutics in one or more disease areas with an interest
in pursuing a career in Pharmacometrics and/or Systems Pharmacology. The
ideal candidate should possess strong programming skills, excellent written
and verbal communication, good organizational abilities, and team work. A
background and understanding of LCMS method development, basic
pharmacology, pharmacometrics and/or systems pharmacology is preferred as
is hands-on knowledge in using software platforms such as NONMEM, MATLAB,
R, SAS, PK-Sim, GastroPlus, SimCYP or other software/scripting languages is
required. The candidate must be self-directed and self-motivated.

*Center for Pharmacometrics and System Pharmacology (CPSP) Overview *

The CPSP is located in the University of Florida Academic & Research Center
at the Lake Nona Medical City about 5 miles southeast of the Orlando
International Airport. The CPSP provides an academic home to a
multidisciplinary and integrative, quantitative clinical pharmacology
program in drug development and regulatory science. Lake Nona Medical City
is a landmark for Orlando and a premier location for medical care, research
and education. It is anchored by University of Central Florida Medical
School, the Sanford-Burnham Medical Research Institute, the newest VA
Medical Center in the country, the Nemours Children's Hospital, and
University of Florida Academic & Research Center. In addition to the
pharmaceutical industry and the FDA, CPSP will also provide the opportunity
for hard-working and self-motivated candidates to work collaboratively with
a multidisciplinary group of scientists from other institutes and hospitals
in the Orlando area.

*To Apply*

Please send curriculum vitae and contact information for three references t=
Dr. Lawrence J. Lesko, llesko_at_cop.ufl.edu, 6550 Sanger Road Orlando, FL


*Mirjam Trame, **Pharm.D., Ph.D.*

Mobil: +1 (407) 764-0070Email: mirjam.trame_at_gmail.com

Received on Wed Dec 10 2014 - 11:10:30 EST

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